Sialix Inc.

Sialix is a pioneer in glycobiology specializing in sialic acid research, discovery and technology platform solutions for industry and biopharm based on the work of Ajit Varki, MD. Sialix is exploring the role of sialic acid biology in inflammation, oncology, and nutrition.

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January, 2012 : News Release
Production platforms for biotherapeutic glycoproteins. Occurrence, impact, and challenges of non-human sialylation
April 19, 2011 : Press Release
Potential New Blood Test and Treatment for Breast Cancer Announced by Sialix, Inc. And Researchers at The University of California, San Diego
April 19, 2011 : Web Press
Human Xeno-Autoantibodies against a Non-Human Sialic Acid Serve as Novel Serum Biomarkers and Immunotherapeutics in Cancer

Gc-Free Western Blot Kit
This kit provides materials to detect the presence of the non-human sialic acid NGNA attached to glycoproteins of recombinant or natural origin on Western Blots.

Samples to be evaluated are first subjected to polyacrylamide gel electrophoresis (PAGE), and then electrophoretically transferred onto a membrane, typically made of nitrocellulose or polyvinylidene difluoride (PVDF).

This membrane "blot" is then exposed to a solution containing affinity-purified chicken polyclonal IgY antibodies specific for NGNA and compared to a similar blot exposed to an equivalent amount of non-specific chicken IgY to determine NGNA present on the protein.